NAD+ is a real and important molecule, and the interest in it is not manufactured. The gap worth being honest about is between what it does inside a cell and what an infusion has been shown to do for a person — because that gap is where most of the marketing lives.
Nicotinamide adenine dinucleotide is a coenzyme present in every cell you have. It is central to turning food into usable energy, and it is consumed by the enzymes involved in DNA repair and in regulating how cells respond to stress.
Levels fall with age. That observation is well established, and it is the reason NAD+ became interesting to researchers in the first place.
The step that does not automatically follow is the one most often assumed: that raising the level back up by infusion produces the benefits people associate with being younger. That is a hypothesis under investigation, not a settled finding.
Human trials of intravenous NAD+ are small, short, and mostly early-phase. There is credible laboratory and animal work behind the underlying biology, and there is a good deal of reported subjective improvement — mental clarity, energy, mood — from people who have had infusions.
Subjective reports matter, and they are also exactly the kind of outcome most affected by expectation. In a treatment that is expensive, novel and takes hours of quiet sitting, that is worth naming rather than glossing over.
What NAD+ infusion is not: an established treatment for any specific disease, a proven anti-ageing intervention, or something with long-term safety data in healthy people. If you are told it reverses ageing or repairs your DNA, that claim has run well ahead of the evidence.
This is not an argument against having one. It is the information you need in order to decide whether you want to, which is a different thing.
A cannula, and then a slow infusion. Slow is the operative word: NAD+ given quickly commonly causes chest tightness, abdominal cramping, nausea and flushing. These are rate-related and settle when the drip is slowed, which is why the rate is adjusted to what you tolerate rather than fixed in advance.
That is why sessions run long — often a couple of hours or more. A short NAD+ infusion is generally either a low dose or an uncomfortable experience.
You should expect someone to stay with you, to be asked how you feel as the rate goes up, and to have the rate turned down without being made to feel difficult about it.
Pregnancy and breastfeeding, because there is no safety data. Active infection, which should be treated rather than infused around.
Significant heart or kidney disease, where the fluid volume itself is the consideration, and any history of reaction to an infusion.
Anyone whose fatigue has not been investigated. That is the important one, and it is the next section.
Persistent tiredness deserves a diagnosis before it gets an infusion. The common causes in women are specific, testable and treatable: iron deficiency, which can cause profound fatigue well before anaemia shows up, so ferritin matters and not just haemoglobin. Thyroid underactivity. Vitamin B12 or vitamin D deficiency. Undiagnosed sleep apnoea. Depression, which very often presents as physical exhaustion rather than low mood.
In perimenopause, disrupted sleep from night sweats produces exactly the daytime fatigue and mental fog that NAD+ is marketed for — and treating the sleep disruption addresses the cause rather than the sensation.
A blood panel and a proper history cost a fraction of a course of infusions and answer the question. If they come back clear and you still want to try an infusion, that is a reasonable and informed choice. Doing it the other way round is how treatable conditions get missed for months.
Consultation ฿1,500–3,000 depending on complexity, plus the ฿300 clinic service fee. Any treatment is quoted separately before you agree to it.
No residency, referral or Thai insurance is needed. An assessment and a blood panel fit easily inside a short stay, and results are usually back quickly.
You will see a female specialist. Consultations are conducted in English or Thai.
If fatigue or mental fog is what brought you here, a blood panel and a proper history answer more than an infusion will. Message us on LINE and tell us what you have been feeling.
This page is general information, not a diagnosis or a treatment recommendation. Suitability for any treatment is decided individually after assessment, and results vary between individuals. Consultations are conducted in English or Thai. THE FIT CLINIC — 8th Floor, EM Tower, EMSPHERE, BTS Phrom Phong, Bangkok. Open daily 10:00–19:00.