What Is MonaLisa Touch?
MonaLisa Touch is a medical-grade CO2 fractional laser system developed by DEKA, an Italian company with more than 40 years of experience in laser technology. The treatment uses precisely controlled CO2 laser energy delivered through a purpose-designed intravaginal probe to create microscopic channels in vaginal tissue — a process known as fractional photothermolysis.
These micro-injuries stimulate the body's natural healing cascade, triggering the production of new collagen, elastin, and hyaluronic acid within the vaginal mucosa. As collagen remodels and moisture-retaining glycogen levels are restored, the vaginal epithelium thickens, becomes more elastic, and re-establishes its natural lubrication. The result is tissue that more closely resembles its pre-menopausal state — structurally, functionally, and physiologically.
What distinguishes MonaLisa Touch from older ablative lasers is its fractional delivery pattern and the DEKA D-Pulse technology, which controls energy distribution to maximise regeneration while minimising thermal damage to surrounding tissue. This makes it safe enough to perform without anaesthesia and gentle enough to require no recovery period.
Conditions Treated with MonaLisa Touch
MonaLisa Touch was originally developed to address Genitourinary Syndrome of Menopause (GSM) — a cluster of symptoms caused by declining oestrogen levels that affect the vulva, vagina, urethra, and bladder. At THE FIT CLINIC Bangkok, our urogynecology and aesthetic gynecology specialists use it to treat a broad range of related conditions:
- Vaginal dryness and atrophy: Thinning, dryness, and fragility of vaginal tissue most commonly seen in peri- and post-menopausal women, and in breast cancer survivors on anti-hormonal therapy.
- Genitourinary Syndrome of Menopause (GSM): The full spectrum of urogenital symptoms linked to oestrogen deficiency, including itching, burning, discharge changes, and urinary urgency.
- Dyspareunia (painful intercourse): Pain or discomfort during sexual activity caused by vaginal dryness and loss of tissue elasticity.
- Mild stress urinary incontinence: Involuntary urine leakage with coughing, sneezing, or physical exertion, related to reduced urethral mucosal support.
- Post-partum vaginal laxity: Mild changes in vaginal tone following childbirth that affect comfort and sensation.
Women who cannot or prefer not to use systemic or topical hormonal therapy — including breast cancer survivors — are often excellent candidates for MonaLisa Touch as a non-hormonal alternative.
The Procedure: What to Expect
Your MonaLisa Touch journey at THE FIT CLINIC begins with a detailed consultation with one of our specialists — Assoc. Prof. Dr. Orawee Chinthakanan, Dr. Athasit Kijimanawat, or Dr. Apichaya Klaikaew — who will review your symptoms, medical history, and suitability for the treatment.
Each treatment session itself takes approximately 5 minutes. The DEKA probe is gently introduced into the vaginal canal and slowly withdrawn while emitting controlled fractional CO2 pulses along the vaginal wall. Most patients describe the sensation as a mild vibration or warmth — no anaesthesia or numbing cream is required.
The standard course is three sessions spaced 4–6 weeks apart. This interval allows the tissue to complete its collagen-remodelling cycle before the next stimulation. Some patients notice improvement after the very first session; the full cumulative effect is typically appreciated 4–8 weeks after the third and final treatment.
There is no downtime. You may experience very mild spotting or a slight watery discharge for 24–48 hours, but normal daily activities — including work — can be resumed immediately. We recommend avoiding sexual intercourse for 3–5 days post-treatment. Annual maintenance sessions are advised to sustain results.
Clinical Evidence & Safety Profile
MonaLisa Touch is one of the most thoroughly studied vaginal laser treatments available. The technology holds FDA 510(k) clearance for the treatment of vaginal symptoms, and its safety and efficacy have been evaluated in multiple peer-reviewed clinical trials published in journals including Menopause, Climacteric, and the International Urogynecology Journal.
Key findings from published clinical literature include:
- Statistically significant improvement in vaginal dryness, burning, itching, and dyspareunia after a three-session course
- Histological evidence of increased collagen density, improved epithelial thickness, and restoration of healthy vaginal pH
- Patient satisfaction rates consistently reported at 90% or above across multiple independent studies
- Sustained improvement at 12-month follow-up in cohort studies, with no serious adverse events reported
- Demonstrated benefit in breast cancer survivors and women who are contraindicated for oestrogen therapy
At THE FIT CLINIC Bangkok, MonaLisa Touch is performed exclusively by qualified urogynecology and aesthetic gynecology specialists, ensuring both clinical rigour and patient comfort throughout every session.
Book Your MonaLisa Touch Consultation
Speak with a specialist at THE FIT CLINIC Bangkok. Open daily 10:00–19:00 at 8th Floor, EM Tower EMSPHERE, Sukhumvit Road.
Book via LINEFrequently Asked Questions
How many MonaLisa Touch sessions are needed?
The standard protocol is three sessions spaced 4–6 weeks apart. Most patients notice significant improvement after the first or second session, with full results typically appreciated 4–8 weeks after completing the series. Annual maintenance sessions are recommended to sustain results long-term.
Is MonaLisa Touch painful?
MonaLisa Touch is designed to be virtually painless. The CO2 laser energy is delivered via a specially designed probe at a gentle intensity that causes no discomfort for the vast majority of patients. No anaesthesia or numbing cream is required, and you can resume normal activities immediately after treatment.
How long does MonaLisa Touch last?
Results from a three-session MonaLisa Touch course typically last 12–18 months. Tissue quality, hormonal status, and lifestyle factors influence longevity. Most patients at THE FIT CLINIC return for a single annual maintenance session to keep the regenerated tissue healthy and maintain symptom relief.
Who is suitable for MonaLisa Touch?
MonaLisa Touch is suitable for women experiencing vaginal dryness, GSM, vaginal atrophy, painful intercourse, or mild stress urinary incontinence — including peri-menopausal women, post-menopausal women, and breast cancer survivors who cannot use hormonal therapy. A consultation with our specialist is needed to confirm suitability.
How much does MonaLisa Touch cost in Bangkok?
Pricing at THE FIT CLINIC Bangkok depends on the individual treatment plan determined at consultation. Please contact us via LINE at lin.ee/thefitclinic or call +66 92 294 6665 for current pricing. A package of three sessions is typically recommended and priced accordingly.